Napoli will have to wait for their first Serie A title in 33 years after being held to a draw by Salernitana at the Stadio Diego Armando Maradona.
They last won the league in 1990 with a Diego Maradona-inspired side adding to their first title three years earlier.
But Boulaye Dia equalised with a left-footed drive six minutes from time.
It silenced an expectant crowd who made a cacophony of noise and set off blue smoke flares inside and outside the stadium, where thousands of fans lined the streets, when Napoli went ahead.
“The players are obviously disappointed at not having made our brilliant fans happy tonight,” Spalletti said.
“But you’ve seen for a while that these points are the hardest ones to get.
“We represent their dreams and that means it’s right that their dreams are realised by us.”
Despite the disappointment Napoli are almost certain to win the title, with just two points needed from their final six games to secure a third Serie A crown.